I have a Pluto+ but had not got around to setting it up yet. It “should” be relatively easy to run through GNURadio and into the USRP channel driver. I wouldn’t think any additional SDR program beyond GNURadio would be needed. See also Set up a personal no-radio access point to Allstar - #20 by KV4FV and Chan_usrp & GNU Radio . USBRadio channel driver could also be used by changing the read() and write() calls in chan_usbradio.c to use a socket to GNURadio instead of to a USB device. LMK how it goes and I would be happy to help with some of these details.